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Best 2022 March Madness Upset Picks

By Hank Blaine

Everyone knows how good Gonzaga, Kentucky, Kansas, and Arizona are. But although those teams should have deep NCAA Touranment runs, the fact that 7 Top 10 ranked teams lost on Feb. 26 proves underrated squads often play well in the NCAA Tournament. Check out a list of five NCAA Tournament teams flying under the radar.

Be sure to keep checking for March Madness odds, along with the latest game previews and guides.

5 Potential 2022 March Madness Upset Picks to Look Out For

READ MORE: Best 2022 March Madness Cinderella Picks

Purdue loses in the second-round

The Boilermakers are a potential 1-seed, but even if Purdue wins the Big Ten Conference Tournament and secures a 1, they will fall in the second round. We don’t even have to know which team Purdue plays in the second round. Jaden Ivey and Zach Edey will be too exhausted in their Round 2 game to lead the Boilermakers to the Sweet 16.

Michigan State loses in the first round

Purdue will disappoint their fans by losing in the first round. Michigan State will disappoint their fans by losing in the first. Sparty should have a deep Big Ten Conference Tournament run, which is one of the reasons they end up a 6-seed or 7-seed in the NCAA Tournament, which means MSU will enter their first tourney game the chalk.

But Michigan State won’t beat their first round opponent. The Spartans are a hard trying, tough, team. Like Purdue, though, they will enter March Madness tired. Not only that, but MSU will face a team that is almost on their level.

Kansas won’t make the Sweet 16

The Jayhawks are one of the best teams in the nation. Even if Kansas loses their conference tournament, and they could because Baylor is the Big 12’s best team, the Jayhawks will be no worse than a 2-seed in the NCAA Tournament.

As a 2-seed, Rock Chalk should have an easy road to the Elite Eight. But it won’t be because if Kansas ends up a 2, they will end up facing a team like Creighton, or Marquette, or Iowa State, or Rutgers, or even a top ACC team like Wake Forest.

If Kansas is a 1-seed, they could end up facing a team like St. Mary’s, or Seton Hall, or Xavier, or Notre Dame in the second-round. All the teams mentioned can beat Kansas if top player Ochai Agbaji has a bad shooting night.

Two 5-seeds lose to 11-seeds in the First Round

5-seeds are always shaky. This season, they should be especially shaky because squads like Alabama, UConn, USC, LSU, and Iowa are potential 5-seeds. Not only that, but potential 11-seeds include Loyola Chicago, Memphis, TCU, underrated Davidson and historical ACC power North Carolina. Like what happens in every NCAA Touranment, the 11-seeds in this year’s tourney will almost be on the same level as the 5-seeds.

Wake Forest is the ACC’s lone Sweet 16 team

Duke should make the Sweet 16, right? Duke, though, has a tendency to lose focus in the NCAA Tournament, and they don’t have the same guard play that Wake has. Top Wake Forest guard Alondes Williams is one of the best in the nation. The 6’ 5 and 210 pounds senior averages 19.4 points, 6.7 boards, and 5.1 assists while shooting close to 52% from the field. Williams is an excellent leader. The Demon Deacons will follow the senior to the Sweet 16 while Duke’s lack of dominating guard play will lead the Blue Devils to a second-round exit.

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This is just one of the many sports betting guides that you can read here at Nitrobetting news. Stay tuned for more 2021-22 NCAAB season previews and articles, and don’t forget to check out the latest college basketball odds on our online BTC sportsbook.

*All odds stated are subject to change without prior notice.