On Wednesday, Chelsea hosts Lille in one of the most intriguing Champions League Round of 16 soccer matches. The Blues rate as one of the top teams in the world, while Lille has had a tough time in Ligue 1. Will Lille turn their form around enough to take down Chelsea, or will the Blues get it done on their field? Check out odds, analysis, and a free pick for Chelsea versus Lille.

Nitrobetting brings you the Chelsea vs. LOSC preview, covering everything you need to know about the contest. Below, you will find event details, the latest Soccer odds, and crucial team and player statistics. More than that, we help you lock in on the best picks by providing timely betting trends and expert predictions. Check out for more sports betting odds and lines at our online Bitcoin sportsbook!

Chelsea vs. LOSC 2022 Champions League Round of 16 Info

#UCL action on home soil comes next! ? pic.twitter.com/gvQVK7ppNO

— Chelsea FC (@ChelseaFC) February 21, 2022

• When: Tuesday, February 22, 2022, 3:00 PM ET
• Where: Stamford Bridge, London, England
• TV: CBS
• Live Stream: DAZN.com
• Soccer Odds: Chelsea (-357) / LOSC (+120) / Draw (+417)

READ MORE: Villareal vs. Juventus 2022 Champions League Odds & Preview (Feb. 22)

Why is Chelsea a safe bet to win?

The Blues are on a roll. Chelsea’s last loss happened on Jan. 15, and it was 1-0 versus arguably the best club squad on the planet, Manchester City. Since the loss, the Blues show a 2-0 victory over Tottenham, the draw versus Brighton, and 4 straight wins, including a victory against Al Hilal and a win versus Brazilian Serie A team Palmeiras, to snag the FIFA Club World Cup trophy. Chelsea returns to Stamford Bridge for this match. Expect the Blues to be ready to grab an aggregate lead with a victory.

Possible Line-Up

• Mendy
• Christensen
• Silva
• Rudiger
• Azpilicueta
• Jorginho
• Kovacic
• Alonso
• Ziyech
• Havertz
• Werner

Chelsea’s Last 5

• Win – 0-1 vs. Crystal Palace
• Win – 0-1 vs. Al Hilal
• Win – 2-1 vs. Plymouth Argyle
• Win – 2-0 vs. Tottenham
• Draw– 1-1 vs. Brighton & Hove

Why is LOSC a safe bet to win?

Since a 5-1 loss to Paris Saint-Germain earlier in the month on Feb. 5, Lille has picked it up, beating Montpellier 1-0 and drawing 0-0 with Metz. More importantly, those two matches were versus Ligue 1 rivals. Lille picks it up in Champions League play. The French League squad fell to Salzburg in their first Champions League match before exacting revenge over Salzburg and drawing and beating Wolfsburg and drawing and beating Sevilla. Sevilla is a quality squad. So we shouldn’t look past Lille’s victory over the La Liga team. If Chelsea isn’t at their best, Lille could surprise.

Possible Line-Up

• Jardim
• Celik
• Fonte
• Botman
• Gudmundsson
• Weah
• Andre
• Sanches
• Bamba/li>
• David
• Yilmaz

LOSC’s Last 5

• Draw – 0-0 vs. Mainz
• Win – 1-0 vs. Montpellier
• Loss – 1-5 vs. Paris Saint-Germain
• Loss – 2-0 vs. Brest
• Win – 3-1 vs. Lorient

Chelsea vs. LOSC Betting Prediction

No doubt, Lille will play tough. Lille beat Paris Saint-Germain to win the Ligue 1 title last season. Not only that, but Lille steps it up the better their rival. If Chelsea were a mediocre team, Lille would be a definite play against.

Lille for sure has a chance. But Thomas Tuchel’s team is sneaky good. Chelsea almost never dominated their opponent. Instead, they play smart soccer by maintaining possession and only taking shots on goal.

Chelsea doesn’t waste shots, which makes them very difficult to beat. What does it mean? Chelsea will play a defense first match, lulling Lille into a slumber, before counter attacking and grabbing a goal. Once they score, the Blues will lock down on the defensive side because Tuchel knows road goals mean a lot in the Champions League Round of 16. Blanking Lille and winning by a single goal is more important than winning 2-1. Chelsea wins straight up, Lille is the play on the handicap.

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