Illinois vs. Michigan 2022 College Football Week 12 Odds, Preview & Pick

By Hank Blaine • November 17, 2022

On Saturday, third-ranked Michigan must prevent the look ahead loss. The Wolverines take on a talented Illinois squad seven days before their annual throw down with Ohio State. If Michigan doesn’t pay attention to the Illini, they could suffer a straight up loss. Will the Wolverines keep their mind on business long enough to not only win but also cover the spread?

Before everything else, NitroBetting arms you with everything you need to kick things off on a positive note. Below, we provide event details, team and player statistics, and the latest NCAAF odds. More than that, we go the extra mile and share timely betting trends and predictions that help you secure the best picks. Check out for more sports betting odds and lines, exclusively at our online Bitcoin sportsbook.

Illinois vs. Michigan Game Information

This senior class has made such a profound impact on the program, leaving a legacy that will be remembered for years to come. pic.twitter.com/Qqxl9Melp2
— Michigan Football (@UMichFootball) November 16, 2022

When: Saturday, November 12, 2022, 12:00 PM ET
Where: Michigan Stadium, Ann Arbor, MI
TV: ABC
Radio: 590 The Fan KFNS (Illinois) // 104.9 The Horn (Michigan)
Live Stream: Watch ESPN
College Footall Odds: Illinois (+18) // Michigan (-18)

Why Bet on the Illinois Fighting Illini?

The Illini have a good enough offense to score points versus the Wolverines D. Illinois averages 24.7 points per game. The key for the Illini on offense is to get the rushing attack going. Illinois averages over 184 rushing yards per game. RB1 Chase Brown has rushed for 1,442 yards and has scored 7 TDs.

Quarterback Tommy DeVito, a transfer from Syracuse, likes to target receiver Isaiah Williams. The Illini’s top wideout has caught 64 passes for 553 yards and has caught 6 touchdowns. Illinois has turned the ball over 10 times this season. The Illini offense is good. The defense is great. Illinois’ D ranks first in takeaways with 17. The defense holds opponents to 249.6 yards per game, ranking second. Illinois ranks fifth in passing yards allowed, 161, and eighth in rushing yards allowed, 88.6. The Illini boast the third stingiest defense in the nation. Opponents average 12.5 points per versus Illinois.

Why Bet on the Michigan Wolverines?

The Maize & Blue fields one of the best offenses in the nation. The Wolverines average 41.4 points per game from an average of 460.3 yards.

Michigan’s rushing attack is where the magic happens. The Wolverines rank fourth in rushing yards each game. Michigan averages 251.4 rushing yards each contest. Running back Blake Corum has scored 17 touchdowns and rushed for 1,349 yards. When Corum gets going, he’s tough to bring down.

Quarterback JJ McCarthy doesn’t have eye-popping stats but he’s been effective. McCarthy completes 69% of his passes and has thrown 14 touchdowns to just 2 interceptions.

Michigan fields the top ranked defense in the nation. The Wolverines rank first in both yardsallowed and points allowed per game. Opponents average 232.8 yards per contest versus the Wolverines. Michigan holds their rivals to 11.5 points per game on average.

The Wolverines have forced 8 takeaways. Mike Morris has 7 sacks and Rod Moore has 3 picks.

Illinois vs. Michigan Betting Trends

Illini are 6-1 ATS in their last 7 on the road.
Illinois is 5-2 ATS in the last 7 meetings.
Illini are 6-1-1 ATS in their last 8 following a straight up loss.
Wolverines are 12-3-1 ATS in their last 16 Big Ten games.
Michigan is 3-1-1 ATS in their last 5 at home.
Wolverines are 5-0-1 ATS in their last 6 games in November.

Illinois vs. Michigan Expert Betting Predictions

In their last 2 games, Illinois hasn’t played well. The Illini lost to Michigan State on Nov. 5. Then in their very next game, the Illini fell to Purdue. Illinois’ defense gave up 23 to Michigan State and 31 to Purdue. The question is was Illinois’ lackluster performances due to the Illini being exposed? If so, Michigan will roll.

If not, Illinois will have a shot to pull off the upset win. Michigan can’t help but think about Ohio State. If it makes Wolverines fans feel any better, Ohio State will be thinking about Michigan.

But the Buckeyes take on a much worse team than Illinois in Maryland. If the Illinois defenses bounces back, this game will be close. Illinois shouldn’t win, but the Illini will put a scare into the Michigan faithful.

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*All stated odds are subject to change without prior notice.