Ole Miss vs. Alabama 2021 College Football Week 5 Odds, Preview & Pick

By Hank Blaine • September 30, 2021

One of most underrated but feverish rivalries in college football takes place on Saturday when Lane Kiffin coached Ole Miss heads to Tuscaloosa to throw down against the 1-ranked Alabama Crimson Tide. So far, oddsmakers and college football handicappers are all over the Tide. Players have pushed Bama to -15. Will Nick Saban’s crew cover the big spread? Or will the Rebels keep this one closer than the number? Check out more information, a look at both teams’ offense and defense, and a pick for Ole Miss versus Alabama.

With more college football action coming your way, the NitroBetting team arms you with everything you need to secure the best picks. Below, you will find essential event details, team and player statistics, and the latest College Football odds. On top of that, you get access to timely betting trends and our very own expert betting predictions. Be sure to check out for more sports betting odds and lines, exclusively at our online Bitcoin sportsbook.

Ole Miss vs. Alabama Game Information

Kiffin vs. Saban.
Corral vs. Young.@OleMissFB vs. @AlabamaFTBL.

Doesn't get much better than this! #MartyAndMcGee #SECNation pic.twitter.com/9ARAH1Cxq1
— SEC Network (@SECNetwork) September 30, 2021

When: Saturday, October 2, 2021, 3:30 PM ET
Where: Bryant-Denny Stadium, Tuscaloosa, Alabama
TV: CBS
Radio: KTXT-FM (Texas Tech) / WZST-FM Jack FM 100.9 (West Virginia)
Live Stream: CBS Sports Live
College Football Odds: Ole Miss (+14.5) / Alabama (-14.5)

Why Bet on the Ole Miss Rebels?

The Rebels field the best offense in the nation. Ole Miss averages 635.3 yards per. The Rebels score 52.3 points each game. Both stats are first in the country. For Ole Miss, it all starts with Heisman Trophy favorite Matt Corral. The Rebels’ QB1 has thrown 9 touchdowns and 0 interceptions. He’s thrown for 997 yards when completing 68.8% of his passes.

But although Corral is terrific, Ole Miss isn’t a one-dimensional offense. The Rebels average 298.7 yards on the ground, making it difficult for defenses to adjust to the passing attack.

The Rebels’ D isn’t spectacular. But it has played well this season. Ole Miss allows 344.7 yards per game. Opponents average 208.7 passing yards and 136 rushing yards each contest. Defensive lineman Sam Williams has emerged as a star. Williams has 4 sacks in 3 games. He will be counted on to stop Alabama’s rushing attack and force the Crimson Tide to throw.

Why Bet on the Alabama Crimson Tide?

Alabama’s offense begins and ends with quarterback Bryce Young. The sophomore is completing 72.1% of his passes. He’s thrown for 1,124 yards. Young’s TD-to-INT ratio is a ridiculous 15-to-1. Bama averages 46.4 points per. Like Ole Miss, the Crimson Tide isn’t one dimensional. Young throws for 313.8 yards each game. Bama rushes for 151.8 each contest.

Bama’s defense has been rock solid this season save for allowing Florida to score 29 points in a close 31-29 victory. To be fair to the Tide, the game happened in The Swamp, on the Gators’ home field.

It’s tough for any team to win in The Swamp. If we throw out the Florida game, the Tide’s defense has rolled. Alabama held Miami to 13 points in their Sep. 4 blowout victory over the Hurricanes. Overall, the Tide allows 17.5 points per from 283.8 yards each game.

Ole Miss vs. Alabama State Betting Trends

Rebels are 6-0-1 ATS versus a team with a winning record
Ole Miss is 6-2 ATS in the last 8 meetings in Alabama
The total went over in 11 of Ole Miss’s last 16 games played in October.
Alabama is 9-2 ATS in their last 11 home games
Crimson Tide is 1-4 ATS versus a team with a winning record
The total went over in 5 of Alabama’s last 6 games against Mississippi.

Ole Miss vs. Alabama Expert Betting Predictions

This should be a great game. But Alabama has big advantages. Lane Kiffin used to coach for Nick Saban. Kiffin ran the Tide’s offense. Don’t think for a moment that Saban won’t put together a game plan to at least slow down Corral and the Rebels’ offense.

Almost as important? Ole Miss gave up 24 points to Louisville, 17 to Austin Peay, and 21 to Tulane, which means Mississippi’s defense is probably worse than we believe. The Rebels’ best chance of winning is to turn this into a shootout. But Bryce Young is more unstoppable than Matt Corral.

In addition, Bama running back Brian Robinson Jr. averages 5.6 yards per carry. Don’t be surprised if Crimson Tide offensive coordinator Bill O’Brien calls Robinson Jr.’s number throughout this game.

Alabama will attempt to keep Matt Corral on the field. Then, when the moment is perfect, Bryce Young will do his thing and the Tide wills start to roll. Trends favor Ole Miss to cover. But Alabama has advantages that make them the play.

NCAAF Week 5 Pick: Alabama Crimson Tide -15

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*All odds stated are subject to change without prior notice.