Rams vs. Colts 2021 NFL Week 2 Odds, Preview and Prediction

By Carlos Chacon • September 14, 2021

The Los Angeles Rams travel to Indiana to face the Indianapolis Colts in Week 2 of the 2021 NFL season. It’s been a tough opening week for the Colts after suffering a 28 to 16 loss in the hands of Seattle. Despite having home-field advantage, the team failed to overcome a more resilient Seahawks team. Nonetheless, the team will try to bounce back from their loss and turn things around with the help of their fans.

Meanwhile, the Rams enjoy their first regular-season victory against the Chicago Bears. The team continues to enjoy success following Sean McVay’s introduction and hopes to complete a deeper postseason run after failing to get past the Packers in the Divisional round last season.

NitroBetting gears up as we enter the second week of the 2021 NFL season. In this preview, we give you a closer look at the Rams vs. Colts contest. Find event information, team and player statistics, and the latest 2021 NFL betting odds. More than that, we arm you with timely betting trends and predictions to help you lock in on the best picks. Don’t forget to check out the latest 2021 NFL odds at out online Bitcoin sportsbook.

Rams vs. Colts Game Information

Just going to leave this here ? pic.twitter.com/JmmYWWsjrq
— Los Angeles Rams (@RamsNFL) September 13, 2021

When: Sunday, September 19, 2021, 1:00 PM ET
Where: Lucas Oil Stadium, Indianapolis, Indiana
TV: FOX
Radio: KSPN 710 AM (Rams) / 1070 The Fan (Colts)
Live Stream:NFL Game Pass
NFL Odds: Los Angeles Rams (-4) / Indianapolis Colts (+4)

Why Bet on the Los Angeles Rams?

Although the Rams failed to win any of their preseason games, it’s great to see the team show its full potential as soon as the regular season took off. The Rams are coming from a 34-14 win against the Bears, which was headlined by Matthew Stafford. The quarterback logged 321 yards on 20 of 26 passing, including three touchdowns. Stafford spared no time following his move from the Detroit Lions as he proved his worth to the team.

Giving him a helping hand is Cooper Kupp, who closed the game with 108 yards on 7 receptions and a touchdown, while Van Jefferson and Tyler Higbee combined for 148 yards and 7 receptions, with the former securing a touchdown. Furthermore, Darrell Henderson rushed for 70 yards on 16 carries and a touchdown.

Defensively, Jalen Ramsey topped the unit with 9 tackles (7 solo), while Jordan Fuller had 11 tackles (6 solo). Justin Hollins closed the night with 8 tackles and 2 sacks. David Lon also had an impressive night with 5 solo tackles and an interception. By the end of the night, the Rams forced 2 turnovers and capitalized on the Bears’ errors to make the game out of reach for their opponents.

Why Bet on the Indianapolis Colts?

The Indianapolis Colts were led by newly acquired quarterback Carson Wentz. In their losing efforts, the 28-year-old was able to record 251 yards on 25 of 38 passing, including a pair of touchdowns. They outplayed the Seahawks 71 to 53 and were not far behind in total yards with 336 yards as opposed to their opponents’ 381 yards. Jonathan Taylor led the receiving end with 60 yards on 6 receptions, while Nyheim Hines documented 48 yards and 6 receptions.

Zach Pascal also had a productive night, registering 43 yards on 4 receptions and two touchdowns. Furthermore, Taylor topped the rushing side as well. The 22-year-old running back finished with 56 rushing yards on 17 carries.

It was a testing night for the team as the Seahawks’ offense imposed themselves from start to end. On defense, Khari Willis took charge and closed the game with 7 tackles (6 solo), while Bobby Okereke was not far behind with 7 tackles (5 solo). DeForest Buckner and Kenny Moore II had one sack each and combined for 9 tackles. Ultimately, if they want to overcome the Rams on Sunday night, the Colts have to do more on the defensive end.

Rams vs. Colts Betting Trends

The Rams are 3-2 in their last 5 away games.
The Rams are 3-2 against the spread in their last 5 away games.
The totals have gone over in 4 of the Rams’ last 5 away games.
The Colts are 3-2 in their last 5 home games.
The Colts are 1-4 against the spread in their last 5 home games.
The totals have gone under in 3 of the Colts’ last 5 games.

Rams vs. Colts Expert Betting Predictions

This is going to be another test for Indianapolis, but there’s a good chance that the team covers the spread. Getting the win might take more out of the team, but it remains within reach as long as they remain consistent on both ends of the field. Meanwhile, the Rams enjoy a strong opening night and will take it on the road as they face the Colts. With a solid lineup and good team chemistry, they enter the contest as favorites. We expect a tight game between the two packed with plenty of action.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.