NFL scheduled great matchups for Week 15. The action starts on Thursday when the Kansas City Chiefs take on the Los Angeles Chargers at SoFi Stadium in Inglewood. The KC versus LAC contest made our NFL Week 15 top picks list. Also on the list is Arizona at Detroit and the Tampa Bay Buccaneers hosting the New Orleans Saints. Check out NFL odds, analysis, and free picks for eight of the best games in NFL Week 15.

Top 2021 NFL Week 15 Betting Picks

NFL Power Rankings, Week 15 (by @DanHanzus): Rams, 49ers climb; Ravens slippinghttps://t.co/ITkmbRjhOh pic.twitter.com/zYLJWndd4t

— Around The NFL (@AroundTheNFL) December 15, 2021

READ MORE: Top Fantasy Waiver Wire Pickups for 2021 NFL Week 15

Thursday, Dec. 16

Kansas City Chiefs vs. Los Angeles Chargers

• 2021 NFL Week 15 Odds: Kansas City Chiefs -3

The KC defense hasn’t yielded more than 9 points in three straight games. Before declaring that the Chiefs’ have gotten lucky, take a look at the offenses KC’s D has dominated. Dallas has one of the best offenses in the league. The Broncos are a decent team and the Raiders average close to 22 points per. KC’s defense is legit, which is why the Bolts will be in some trouble on Thursday night.

NFL Week 15 Pick: Chiefs

Sunday, Dec. 19

New York Jets vs. Miami Dolphins

• 2021 NFL Week 15 Odds: Miami Dolphins -8.5

The Jets are a mess of a team. There’s no other way to describe Zach Wilson and his mates. While the Jets are horrible, the Miami Dolphins have quietly won 5 straight and are in the thick of the AFC’s wildcard race. The Fins face some tough customers in the ensuing weeks. But in Week 15, Miami should have no trouble blowing out their AFC East rival.

NFL Week 15 Pick: Dolphins

Arizona Cardinals vs. Detroit Lions

• 2021 NFL Week 15 Odds: Arizona Cardinals -13

If you’re looking for why Arizona fell to the Los Angeles Rams on Monday night, here’s your answer. Kyler Murray and the Cards shot themselves in the foot. Murray threw two picks, one of which was in the red zone, and Kliff Kingsbury made a couple of boneheaded calls. Also, AZ didn’t once hide their blitz. So, yeah, Matthew Stafford took advantage. Jared Goff won’t. Detroit doesn’t have the players to hang with AZ. Look for the Cardinals to win this by at least 16 points.

NFL Week 15 Pick: Cardinals

Tennessee Titans vs. Pittsburgh Steelers

• 2021 NFL Week 15 Odds: Tennessee Titans -1.5

Pittsburgh’s best defender, T.J. Watt, may miss this due to a groin injury. If Watt doesn’t play, it’s hard to see Pittsburgh beating the Tennessee Titans. Then again, the Titans’ defense yields 250.7 passing yards per. Unless the Steelers make the playoffs, Big Ben has just a few more games in a Pittsburgh uniform. Expect Roethlisberger to lead his team to the moneyline victory.

NFL Week 15 Pick: Steelers

Atlanta Falcons vs. San Francisco 49ers

• 2021 NFL Week 15 Odds: San Francisco 49ers -9.5

Two teams moving in opposite directions clash when the San Francisco 49ers host the Atlanta Falcons. The Niners have won 4-of-5. SF is a legit playoff contender while the ATL is already thinking about next season. 9.5 seems like a lot of points. In this matchup, it isn’t.

NFL Week 15 Pick: 49ers

Seattle Seahawks vs. Los Angeles Rams

• 2021 NFL Week 15 Odds: Los Angeles Rams -4.5

Sure, the Rams have played two fantastic games in a row. But we shouldn’t read too much into either victory. The win against the Jaguars showed nothing. Beating Arizona in the desert showed a lot. Still, the Cardinals helped the Rams to their 7 points win. Seattle is 2-0 SU and ATS in their last couple of games. Murray couldn’t expose the Rams’ less than stellar secondary. The Seahawks should have no trouble doing so on Sunday. That doesn’t mean Seattle wins. It does mean Russell and his mates cover.

NFL Week 15 Pick: Seahawks

Green Bay Packers vs. Baltimore Ravens

• 2021 NFL Week 15 Odds: Green Bay Packers -4.5

John Harbaugh expects Lamar Jackson to play but even if Lamar suits up, the Ravens should be in trouble. Baltimore’s pass defense isn’t good. So unless Rodgers sits out due to the toe injury, the Packers should easily cover this spread. Simply put, Baltimore isn’t good enough to keep this to within 5 points.

NFL Week 15 Pick: Packers

New Orleans Saints vs. Tampa Bay Buccaneers

• 2021 NFL Week 15 Odds: Tampa Bay Buccaneers -11

Josh Allen used his legs to rally the Buffalo Bills. Allen’s success gives us a clue as to what might happen on NFL Sunday Night Football. Like Josh Allen, Taysom Hill is a running quarterback. He’s a handful, which means unless the Bucs adjust, Sean Payton will call enough Hill running plays to give the Saints a shot at the victory. Much like what happened in Week 14, the Bucs should prevail. However, the Saints will make this much closer than the spread.

NFL Week 15 Pick: Saints

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*All odds stated are subject to change without prior notice.