Upsets aren’t always easy to find in college football. University athletic directors love to pad their teams’ schedules with cupcakes. So finding upsets isn’t an easy task. But this season, there are five upset possibilities that should be on everyone’s radar. Check out a list of the five most probable and meaningful upsets likely to happen in the 2022 college football season.

Predicting 2022 College Football’s Biggest Betting Upsets

Will Clemson regain the ACC crown? ????@ESPNMcGee takes a look at where the conference stands in 2022. pic.twitter.com/nN2MxYJ1Dx

— ESPN College Football (@ESPNCFB) August 16, 2022

READ MORE: 2022 College Football Teams That Won’t Make the Playoffs

Cincinnati beats Arkansas – Sep. 3

Many believe the Arkansas Razorbacks can contend in the deep SEC, which is why the Hogs are a favorite to beat Cincinnati on Sep. 3. But although Arkansas is deep because players like quarterback KJ Jefferson return, Cincinnati can pull off the upset win.

Senior transfer quarterback Ben Bryant comes over from Eastern Michigan. He’s not Desmond Ridder, but he has experience. Not only that, but the Bearcats’ offensive line boasts 4 seniors and a junior center.

Cincinnati lost some players to the NFL, but the drop off won’t be as significant as many believe. The Bearcats grab the straight-up win.

NC State takes down Clemson – Oct. 1

Clemson could bounce back and win the ACC, but it feels like 2022 is the same old story. Every season, oddsmakers overvalue Dabo Swinney’s team. In the past couple of seasons, Clemson hasn’t delivered.

NC State should field a great offense and great defense. The Wolfpack’s D won’t be as good as Clemson’s, but the offense should be better than Clemson’s. The Tigers’ offensive line was horrible in 2021. Not only that, but quarterback D.J. Ugaialelei has a lot to prove. NC State can beat Clemson.

Michigan falls to Penn State – Oct. 15

Michigan played great football last season. Coach Jim Harbaugh finally got past rival Ohio State, the Wolverines won the Big Ten Championship, and Michigan secured their first College Football Playoff berth.

Heading into the season, the Wolverines rank 6th according to the Associated Press. Rival Penn State isn’t in the Top 25 per the AP. That will change on Oct. 15. After a tough season, the Nittany Lions should bounce back. The bounce back will include upsetting Michigan in Ann Arbor.

Nittany Lions quarterback Sean Clifford is a redshirt senior. Clifford should have much more time throwing the football against the Wolverines’ D this season than he did last season because Aidan Hutchinson is a Detroit Lion. Also, Michigan lost more than Hutchinson, which means the Wolverines are overrated heading into the season.

Florida pulls off the upset against Georgia – Oct. 29

This is the biggest betting upset on the list. Georgia is second choice to win the National Championship after SEC rival Alabama. The Bulldogs return enough talent on offense to be a top four team.

Plus, although a bunch of talent left to the NFL on defense, Kirby Smart is one of the best recruiting head coaches on defense in the nation. Smart can plug and play, which means Georgia should have one of the better defenses in the country by the time this game happens.

Still, new Florida Billy Napier knows what he’s doing. The former Louisiana Ragin’ Cajun boss used the transfer portal to build a right away SEC East division contender.

Supremely skilled quarterback Anthony Richardson plays behind a line that boasts 3 seniors and a couple of juniors. The defense should be good enough to contain Stetson Bennett and the Dawgs’ offense. The Gators pull off the biggest shocker of the season.

Baylor upsets Oklahoma – Nov. 5

Oklahoma has gone through too many changes to beat the defending Big 12 Champions. Brett Venables, Clemson’s former defensive coordinator, will be a good head coach for the Sooners. But Oklahoma lost starting quarterback Caleb Miller to Lincoln Riley and USC. The Sooners also lost players on their defense. On the plus side, Venables transferred UCF QB Dillon Gabriel.

However, Gabriel could play well and Baylor should still win this game. Blake Shapen is one of the best quarterbacks in the nation. The Bears’ defense will rock and Baylor rushes the ball well. The Bears pull off the upset win.

Where to Bet On College Football with Bitcoin

College Football odds are available all year round here at Nitrobetting. Create a Nitrobetting account now to win tons of Bitcoin from the 2022 College Football offseason with our up-to-date NCAAF futures odds, as well as our special Bitcoin Squares and Picks contests throughout the upcoming regular season!

Check out our latest sports betting guides for the 2022 College Football season. Stay tuned for more football previews and articles, and don’t forget to check out the latest NCAAF betting odds at our online Bitcoin sportsbook.