Broncos vs. Seahawks 2022 NFL Week 1 Odds, Preview & Pick

By Hank Blaine • September 8, 2022

The first Monday night game of the 2022 NFL season is a homecoming for Broncos quarterback Russell Wilson as Denver visits Seattle. Of course, the Seahawks traded arguably the best player in franchise history there in the offseason.

Nitrobetting is ready to equip its bettors with the latest news, odds, and special features for the entire duration of the 2022 NFL season. This time, let’s take a closer look at the upcoming Week 1 divisional showdown between the Denver Broncos and the Seattle Seahawks.

Broncos vs. Seahawks Game Information

This is #BroncosCountry.

Let's Ride. ???? pic.twitter.com/i69yolBszl
— Denver Broncos (@Broncos) September 8, 2022

When: Monday, September 12, 2022, 8:15 PM ET
Where: Lumen Field, Seattle, WA
TV: ESPN
Radio: KOA 850 AM (Broncos) // KIRO Newsradio 97.3 FMc (Seahawks)
Live Stream: NFL Game Pass
NFL Odds: Broncos (-6.5) // Seahawks (+6.5)

Why Bet on the Denver Broncos?

Back in March, the Broncos received nine-time Pro Bowl quarterback Russell Wilson and a fourth-round pick in exchange for tight end Noah Fant, quarterback Drew Lock, defensive end Shelby Harris, 2022 and 2023 first-round picks, 2022 and 2023 second-round picks and a 2022 fifth-round pick.

Wilson has recorded more wins in his first 10 seasons, including the postseason, than any quarterback in NFL history. During his 10 years in Seattle, he led the Seahawks to eight seasons with double-digit wins, eight playoff appearances, two Super Bowl berths and a Super Bowl XLVIII win over the Broncos. The only losing season in his career was last year when Wilson missed a few games injured.

The New York Giants and New Orleans Saints also looked into trading for Wilson. The QB, though, had essentially already narrowed his potential destinations to the Broncos, one of the four teams his agent, Mark Rodgers, had publicly identified as preferred landing spots the year before.

One of the biggest blockbuster trades in NFL history sets up Monday night’s Week 1 reunion at Seattle’s Lumen Field, where Wilson and the Broncos will face the Seahawks and his former backup Geno Smith.

First-year Denver head coach Nathaniel Hackett decided to rest 99% of his starters this preseason, which triggered some criticism and hand-wringing in the media. Hackett’s preseason approach had its desired effect: the Broncos’ first-teamers were mostly preserved from injury. The health of two projected starters, and their availability for Week 1, is still somewhat up in the air.

The Broncos have hoped to have inside linebacker Jonas Griffith, one of the few projected starters to receive playing time this preseason (only to suffer a dislocated elbow on his second snap), and right tackle Billy Turner available in Seattle. Both have been practicing this week so that bodes well.

The Broncos have impressive talent at the top of their cornerback depth chart, but the depth is a little shallow behind the top three options. Pat Surtain and Ronald Darby are the locked-in starters on the outside with experienced vet K’Waun Williams playing on the inside. Behind them, the Broncos have promising — but unproven — rookie Damarri Mathis and newly-signed veteran Darius Phillips. As a rookie, Surtain showed a ton of ability. He had four interceptions and only allowed a 51% completion rate and a 61.3 passer rating.

“We have five corners, that’s typically what teams [keep], five or six,” general manager George Paton said last week. “I feel good.”

Why Bet on the Seattle Seahawks?

Smith beat out Drew Lock to replace Wilson as Seattle’s starting QB. It was clear from the moment Smith re-signed with the Seahawks that it was his job to lose. He spent two seasons as Wilson’s backup and has 34 career starts, giving him a head start on Lock from day one of the competition. In nine preseason possessions, Lock threw three interceptions and one touchdown and the Seahawks scored 20 points.

“Geno, he knows our stuff and he does really well and he understands it and he commands everything that we’re doing,” Carroll said. “He’ll give us the best chance to play great football right off the bat.”

The Seahawks also said goodbye to legendary icon and potential future Hall of Famer linebacker Bobby Wagner this offseason. Wagner, selected with Wilson on the second day of the 2012 draft, was the last remaining member of the star-studded defenses that led Seattle to its lone world championship and a return trip to Super Bowl XLIX after the 2014 season. Wagner was coming off a 170-tackle season that earned him his eighth Pro Bowl nod in 10 seasons.

The Seahawks lost 10 games last year, the most for the Seahawks since the 2009 season. It was also the Seahawks’ first losing season since 2011, and just their second time missing the playoffs in the past 10 years. Seattle had five decided by 3 or fewer points, all of which the Seahawks lost, a reminder of how small the margin can be between a playoff season and a losing record. Seattle’s point differential overall was plus-29, making the Seahawks one of only two teams, along with Denver, to have a losing record with a positive point differential.

Broncos vs. Seahawks Betting Trends

Denver is 2-4 ATS in their last 6 games.
Broncos are 1-5 SU in their last 6 games.
The total went under in 8 of Denver’s last 11 games.
Seattle is 4-2 ATS in their last 6 games.
Seahawks are 4-2 SU in their last 6 games.
The total went over in 5 of Seattle’s last 6 games.

Broncos vs. Seahawks Expert Betting Predictions

Broncos win by a TD to cover.

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*All stated odds are subject to change without prior notice.