Buccaneers vs. Cowboys 2022 NFL Week 1 Odds, Preview & Pick

By Hank Blaine • September 7, 2022

It’s a marquee matchup indeed for the first Sunday night game of the 2022 NFL season as Tom Brady and the Tampa Bay Buccaneers visit the Dallas Cowboys – both won their divisions last year and both may well again this year.

If a Week 1 matchup between these clubs sounds familiar, it’s because the started the 2021 season in Tampa in the Kickoff Game when the Bucs were defending Super Bowl champions. It was a fabulous game won by Tampa Bay 31-29 on a last-second field goal by Ryan Succop. Brady threw for 379 yards and four touchdowns.

Succop’s field goal came after Greg Zuerlein put the Cowboys ahead with a 48-yarder with 1:24 to go. Dak Prescott threw for 403 yards and three TDs for Dallas.The Cowboys have never beaten Brady, who improved to 6-0 against them, with five of the victories coming during his historic 20-year run with the New England Patriots.

Nitrobetting is ready to equip its bettors with the latest news, NFL betting odds, and special features for the entire duration of the 2022 NFL season. This time, let’s take a closer look at the upcoming Week 1 clash between the Tampa Bay Buccaneers and the Dallas Cowboys.

Buccaneers vs. Cowboys Game Information

Our work is unfinished. So let's get to it.

Narrated by @TomBrady. pic.twitter.com/tn5gYjKi6j
— Tampa Bay Buccaneers (@Buccaneers) September 5, 2022

When: Sunday, September 11, 2022, 8:20 PM ET
Where: AT&T Stadium, Arlington, TX
TV: NBC
Radio: WXTB, 97.9 FM Tampa (Buccaneers) // 590 The Fan (Cowboys)
Live Stream: NFL Game Pass
NFL Odds: Buccaneers (-2) // Cowboys (+2)

Why Bet on the Tampa Bay Buccaneers?

This could well be Brady’s last season opener amid reports his wife Giselle Bundchen is so angry that he unretired this summer that she might be considering divorce. It will be the Bucs debut of future Hall of Fame receiver Julio Jones, signed as a free agent in the offseason. He appeared in just 10 games last year with the Titans because of injuries and had career lows with 31 receptions for 434 yards and just one touchdown reception. It was the second straight season in which Jones was limited by injury. He appeared in just nine games for the Falcons in 2020. Jones leads the NFL in receiving yards since 2014 and Mike Evans leads the NFL in touchdown catches, and they’re both now on the same team. It’s not clear if Brady will have another former Pro Bowl receiver in Chris Godwin as he works his way back from a torn ACL that ended his 2021 season early. Speaking on a podcast, Godwin said “I don’t think any of us know that yet” when asked if he’d play in Week 1. “I would imagine I have the final say. It’s going to come down to feel … In the grand scheme of things, it doesn’t matter that much. I would love to be there for the entire season, but I think what’s more important is being there for the second half of the season.” Godwin has been practicing. Tampa Bay took a big hit early in training camp when Pro Bowl center Ryan Jensen suffered a serious injury that might cost him all of 2022. He will be replaced by Robert Hainsey, a third-round pick out of Notre Dame last year. Hainsey appeared in nine games as a rookie and while it will be difficult to replace Jensen, Brady believes Hainsey is capable of proving himself. “He worked hard last year [and] really gained the trust of a lot of people. He’s got to go earn it,” Brady said. “Like all of us, it’s not what you did in the offseason, it’s how good of a football player are you? It’s to be determined for all of us.” Todd Bowles, a former Cowboys defensive coordinator, took over the head coaching spot this offseason in Tampa after Bruce Arians’ retirement and subsequent move into the front office. Bowles spent four seasons in New York with the Jets and won just 26 of his 67 games during that time.

Why Bet on the Dallas Cowboys?

The Cowboys will be without eight-time Pro Bowl left tackle Tyron Smith for most of the season with a severe hamstring injury. Rookie Tyler Smith will take his place. Considered raw for a first-round lineman, Smith was penalized 25 times in his last 21 games at Tulsa. It’s yet another blow for Dallas, which has sneakily lost a lot of talent in the offseason – especially on offense. The team traded Amari Cooper to the Browns for only a fifth-round pick and cap relief. One of their other star receivers, Michael Gallup, is still recovering from a torn ACL suffered late in the 2021 season. And James Washington, whom Dallas signed as a free agent from Pittsburgh, fractured his foot during training camp. Neither will play in Week 1. If there is one unit that does not have many question marks surrounding it for the Cowboys, it would be the defensive side of the ball. In last year’s matchup against the Bucs, the defense forced four turnovers.

Buccaneers vs. Cowboys Betting Trends

The Ravens went 3-5 on the road last season (SU/ATS).
The Ravens are 9-1 in their last 10 meetings against the Jets dating back to 1998 (8-2 ATS).
The totals went under in five of Baltimore’s last seven road games.
The Jets went 3-6 at home in 2021 (4-5 ATS).
The Jets have won three straight contests against AFC North teams not named the Ravens (SU/ATS).
The totals went over in six of the Jets’ last eight home games.

Buccaneers vs. Cowboys Expert Betting Predictions

Bucs 27, Cowboys 24.

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*All stated odds are subject to change without prior notice.