Top MLB Betting Picks of the Week (July 25th, 2022)

By Hank Blaine • July 25, 2022

In Major League Baseball, great matchups happen every week. Our list of the top games start on Wednesday in a subway series between the Yankees and Mets. On Thursday, the Cubs travel to San Francisco to take on the Giants and then on Friday it’s a great NL versus AL clash when the Twins take on the Padres. See below for analysis and free picks for six fantastic MLB games happening from Wednesday through Sunday.

Top MLB Betting Picks of the Week (July 25th, 2022)

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New York Yankees vs. New York Mets

When: Wednesday, July 27, 2022, 7:10 PM ET
Where: Citi Field, Queens, NY
TV: ESPN
Radio: WFAN 66 (Yankees) / WCBS 880 (Mets)
MLB Betting Odds: TBA

The Mets should have this contest in the bag. The New York Yankees send Domingo German to the mound. German is 0-1 with a 15.00 ERA. The Mets counter with ace Max Scherzer. Scherzer is 6-2 with a 2.28 ERA. But even when Scherzer throws well, it doesn’t mean the Mets win. NYM has lost 2 of Scherzer’s last starts and required 10 innings to get past the Cubs in one of the last 4 starts. Backing the underdog Yankees makes sense.

MLB Betting Pick: Yankees

Chicago Cubs vs. San Francisco Giants

When: Thursday, July 28, 2022, 9:40 PM ET
Where: Oracle Park, San Francisco, CA
TV: Marquee Sports Network, NBCS BA
Radio: 670 The Score (Cubs) / KNBR 680 (Giants)
MLB Betting Odds: TBA

Cubs starter Justin Steele has a 4-6 record. Although the record isn’t great, the ERA is. Steele brings a 4.02 ERA into this. The Giants go with Alex Wood. SF’s record with Wood on the mound is spotty. The Giants have beaten the Padres and Brewers, but have lost to the Dodgers, Diamondbacks, and Tigers in the last 5. In 23 at-bats, the Cubs have a .281 average versus Wood. 23 ABs isn’t enough to recommend backing. The likely home chalk gets the nod.

MLB Betting Pick: Giants

Minnesota Twins vs. San Diego Padres

When: Friday, July 29, 2022, 9:40 PM ET
Where: Oracle Park, San Francisco, CA
TV: Bally Sports North, Bally Sports San Diego, MLBN (out-of-market only)
Radio: TIBN (Twins) / KWFN 97.3 (Padres)
MLB Betting Odds: TBA

Twins pitcher Joe Ryan has rocked it this season. Ryan is 7-3 with a 2.89 ERA and a 1.05 WHIP. His ERA in the last 7 days is 1.59. San Diego listed starter Blake Snell is 2-5 with a 4.75 ERA. The Friars have lost 3 of the last 5 Snell starts. The Padres won Snell’s last start. They should lose this one.

MLB Betting Pick: Twins

Milwaukee Brewers vs. Boston Red Sox

When: Saturday, July 30, 2022, 4:10 PM ET
Where: Fenway Park, Boston, MA
TV: Bally Sports Wisconsin, NESN, FS1
Radio: WTMJ 620 (Brewers) / WEEI 93.7 (Red Sox)
MLB Betting Odds: TBA

Milwaukee is 6-3 with a 3.84 ERA. Brewers pitcher Eric Lauer is 6-3 with a 3.84 ERA. Lauer has struck out 103. Boston sends Nick Pivetta to the mound. Pivetta is 8-7 with a 4.35 ERA. The Red Sox starter has a 1.59 ERA in the last 7 days. Lauer’s ERA in the last 7 days is 8.31. Pivetta and the Red Sox have the edge.

MLB Betting Pick: Red Sox

St. Louis Cardinals vs. Washington Nationals

When: Saturday, July 30, 2022, 7:15 PM ET
Where: Fenway Park, Boston, MA
TV: FOX
Radio: KMOX 1120 AM0 (Brewers) / WJFK 106.7 The Fan (Nationals)
MLB Betting Odds: TBA

Hudson is 6-6 with a 4.10 ERA. The ERA isn’t bad, but the Cardinals have lost 4 of Hudson’s last 5 starts. One of the losses was a 4-0 “L” versus the Dodgers on July 14. The Nationals had lost 3 straight Erick Fedde starts. In Fedde’s last, they stepped it up, scoring 4 in a 4-3 win. But the Nats pulled Fedde in that game after he gave up 3 runs before the fifth. Hudson and the Cards can grab a victory. Fedde isn’t pitching better than St. Louis’ starter and Washington should have a tough time winning 2 Fedde starts in a row.

MLB Betting Pick: Cardinals

Cleveland Guardians vs. Tampa Bay Rays

When: Sunday, July 31, 2022, 1:40 PM ET
Where: Fenway Park, Boston, MA
TV: Bally Sports Great Lakes, Bally Sports Sun,
Radio: WTAM 1100 (Guardians) / WDAE 620 AM (Rays)
MLB Betting Odds: TBA

Tampa pitcher Shane McClanahan is dominating. The Rays’ ace has a 10-3 record with a 1.71 ERA. McClanahan should have no trouble getting by Cleveland. The Guardians are undecided on their starter. No matter who ends up on the mound, Tampa Bay has the edge. A run line Tampa victory seems possible.

MLB Betting Pick: Rays

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*All odds stated are subject to change without prior notice.