The best NCAA Men’s College Basketball games of the week start on Wednesday when the NC State Wolfpack takes on the Kansas Jayhawks and the Tennessee Volunteers go against the Butler Bulldogs. Then on Thursday, Duke takes on Oregon State and Michigan State throws down against Alabama. See below for analysis and free picks for six of this week’s top NCAAB picks.

Top NCAAB Betting Picks of the Week (November 21st, 2022)

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1. North Carolina
2. Houston
3. Kansas
4. Texas
5. Virginia
6. Gonzaga
7. Baylor
8. Duke
9. Arkansas
10. Creighton

— NCAA March Madness (@MarchMadnessMBB) November 21, 2022

NC State Wolfpack vs. Kansas Jayhawks

• When: Wednesday, November 23rd, 2022. 12:00pm EST.
• Where: Imperial Arena, Nassau, Bahamas

NC State is 4-0 and 2-2 against the spread. The Wolfpack’s record suggests NC State can hang with Kansas but the truth is that the Pack hasn’t played a team even close to Kansas’ level.

In fact, NC State could be in some trouble on Wednesday if Kansas plays the way so many expect. The Wolfpack’s two non-covers happened in games against Elon and Campbell.

The Jayhawks are 4-0 but only 1-3 against the spread. Kansas’ lone cover happened against Duke. The Jayhawks figure to grab their fifth win and second cover of the season on Wednesday.

NCAAB Betting Pick: Kansas

Butler Bulldogs vs. Tennessee Volunteers

• When: Wednesday, November 23rd, 2022. 7:30pm EST.
• Where: Imperial Arena, Nassau, Bahamas

The Bulldogs are a decent squad. Butler has won 3-of-4 straight up and are 3-0-1 against the spread. But although Butler has played great basketball, the Bulldogs should struggle versus Tennessee.

The Volunteers head into this game after trouncing tough Florida Gulf Coast 81-50. Colorado upset Tennessee in the Volunteers’ second game. The bounce back effort over Florida Gulf Coast implies the Vols are ready to rock it. Tennessee wins and covers.

NCAAB Betting Pick: Tennessee

Duke Blue Devils vs. Oregon State Beavers

• When: Thursday, November 24th, 2022. 3:00pm EST.
• Where: Veterans Memorial Coliseum, Portland, OR

On Thursday, things could go badly for Oregon State. The Beavers take on Duke a game after losing by 13 to Portland State.

Save for a loss to Kansas, the Blue Devils have dominated their opponents. Duke beat Delaware 92-58 in the game before the Nov. 21 contest versus Bellarmine. A similar score, 92 Duke and 58 Oregon State, could happen on Thursday.

NCAAB Betting Pick: Duke

Alabama Crimson Tide vs. Michigan State Spartans

• When: Thursday, November 24th, 2022. 3:00pm EST.
• Where: Veterans Memorial Coliseum, Portland, OR

4-0 Alabama is playing great basketball. The Crimson Tide have also gone 3-1 against the spread.

On Thursday, Bama takes on a Michigan State team that has won 3-of-4 and has covered in 2-of-4. The Spartans beat Villanova 73-71 on Nov. 18. For sure, Michigan State can win this, but the spread line could make Sparty an underlay. Bama gets it done ATS.

NCAAB Betting Pick: Alabama

Iowa Hawkeyes vs. Clemson Tigers

• When: Friday, November 25th, 2022. 7:00pm EST.
• Where: The Arena at Northwest FL St, Niceville, FL

Clemson has played well enough so far this season to go 4-1 straight up. The Tigers, like so many teams in the ACC, build around a suffocating defense that holds opponents to less than 40% from the field.

But Clemson allows close to 38% from three, which isn’t a good stat for the Tigers heading into a game against Kris Murray and the Iowa Hawkeyes.

Murray and the Hawkeyes are 4-0 SU and 4-0 ATS. The Tigers are 1-4 against the spread. So backing Kris and his mates is the way to go.

NCAAB Betting Pick: Iowa

St. Louis Billikens vs. Auburn Tigers

• When: Sunday, November 27th, 2022. 3:00pm EST.
• Where: Neville Arena, Auburn, ALL

It’s early, but St. Louis is shaping up as one of the more unsung squads in college hoops. The Billikens boast a 4-1 straight up record and are 3-2 against the spread. St. Louis takes on Auburn after beating Big East squad Providence 76-73.

The Tigers are 4-0 straight up but just 2-2 against the spread. Like in most games where a ranked SEC team takes on an unranked A-10 squad, Auburn is likely to offer an underlay spread. St. Louis has a real shot to cover.

NCAAB Betting Pick: St. Louis

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READ MORE: Top NCAAB Betting Picks of the Week – November 28th, 2022