Seahawks vs. Colts 2021 NFL Week 1 Odds, Preview and Pick

By Carlos Chacon • September 7, 2021

This weekend, the NFL returns to bring us much-awaited action. Among the list of games is a contest between the Pittsburgh Steelers and the Buffalo Bills. The Steelers are coming off a 12-4 record last season, claiming the top spot in the AFC North. During the preseason, the team performed wonderfully as well, ending their run with 3 wins and one loss.

Meanwhile, the Bills finished a strong run in their previous campaign with a 13-3 record and a first-place finish in the AFC East. Looking at their preseason run, the Bills also stood out with an undefeated 3-0 run.

As another football season unfolds before us, NitroBetting graces you with the latest NFL previews. Find the latest event information, key team and player stats, and the latest NFL betting odds. More than that, we make sure you lock in on the best picks with the aid of our latest betting trends and expert betting predictions. Be sure to check out the latest 2021 NFL Season odds at out online Bitcoin sportsbook.

Seattle Seahawks vs. Indianapolis Colts Game Information

QB Ryan Tannehill, who was activated from the Reserve/COVID-19 list, was back on the practice field today.

Monday Quick Hits ? » https://t.co/6IQ9OAy4zp
— Tennessee Titans (@Titans) September 6, 2021

When: Sunday, September 12, 2021, 1:00 PM ET
Where: Nissan Stadium, Nashville, Tennessee
TV: CBS
Radio: 98.7 FM (Seahawks) / 104.5 FM The Zone (Colts)
Live Stream:NFL Game Pass
NFL Odds: Seahawks (-2.5) / Colts (+2.5)

Why Bet on the Seattle Seahawks?

The Seattle Seahawks retain their starting quarterback Russell Wilson despite facing several trade rumors in the off-season. There’s more pressure on the team to achieve a deeper playoff run this year, and Wilson is one of the names expected to help the Seahawks achieve that.

Offensively, Seattle has the arsenal in receivers DK Metcalf and Tyler Lockett, while running back duties fall in Chris Carson’s hands, who was able to record 1,000 rushing yards two times in the last three seasons. The combination of these players makes for a menacing offense, which is going to be the team’s ace card this season.

Defensively, having Carlos Dunlap II adds to the strength of the unit with a more consistent pass rush from the jump. Meanwhile, Jamal Adams should be more settled in his second year with the team. With Bobby Wagner still in the lineup, together with Quandre Diggs and DJ Reed operating at their best, we could see the Seahawks propel to one of the best defensive teams in the league. As long as the team doesn’t let the pressure get into them, we anticipate a great season for Seattle this year.

Why Bet on the Indianapolis Colts?

Looking at the Colts, we see a team not far from the Super Bowl talks. The team now enters the season with a different quarterback for the fourth-straight season, which might put light on inconsistency issues. Nevertheless, Carson Wentz reuniting with Frank Reich is good news for the team. He gets to play alongside a resilient Jonathan Taylor who is coming off 1,000 rushing yards and 12 touchdowns in the previous season as a rookie.

The backfield goes deeper than Taylor. Behind him are Nyheim Hines and former RB1 Marlon Mack, plus Jordan Wilkins. Still, the bulk of the touches in the rushing attack will be consumed by Taylor.

Previewing the defense, the Colts have two solid players in DeForest Buckner and rookie Darius Leonard. Meanwhile, Zaire Franklin should see more movement at linebacker while rookie Kwity Paye could add more sting to the pass rush.

If everything gains traction and Eric Fisher makes his way back, the Colts might have a shot at taking down the mighty Seahawks in their opening game.

Seahawks vs. Colts Betting Trends

The Seahawks are 3-2 in their last 5 away games.
The Seahawks are 0-5 against the spread in their last 5 away games.
The totals have gone under in all but one of those eight road games from 2020.
The Colts are 3-2 in their last 5 home games.
The Colts 1-4 against the spread in their last 5 home games.
The totals have gone over in 2 of the Colts’ last 5 home games.

Seahawks vs. Colts Expert Betting Predictions

The Indianapolis Colts seem like they have a shot at covering the spread. More than that, there’s also reason to believe that they can keep the game close. With a revamped lineup and good preseason results, the Colts should be a tough opponent for Seattle. At the other end of the spectrum, Seattle steps into the Lucas Oil Stadium as favorites. If the team remains consistent and builds from their last preseason win against the Chargers, they can secure their first win of the season. Ultimately, we are looking at an exciting matchup between the two.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.