2022 NFL Season Top 5 Running Backs

By Jeff Stinger

With the NFL being a pass-happy league these past few years, the running back position is often overlooked despite several of these backs breaking records left and right of late. Nonetheless, here’s a list of the top five running backs poised to have monstrous offensive seasons in 2022; all of whom are strong contenders for this upcoming season’s Offensive Player of the Year award.

Nitrobetting is ready to equip its bettors with the latest news, NFL futures odds, and special features for the duration of the 2022 NFL offseason. This time, let’s count down the five best running backs heading into the 2022 NFL season and their respective odds of winning the coveted 2022 NFL Offensive Player of the Year award to date.

Top 5 Running Backs Heading into the 2022 NFL Season

READ MORE: 2022 NFL Season Top 5 Quarterbacks

Jonathan Taylor

  • 2022 NFL OPOY Award Odds: +900

After a terrific 2021 rookie season, Indianapolis workhorse back Jonathan Taylor would up the ante in a big way in his sophomore campaign. Taylor led the NFL by a mile with his 1,811 rushing yards in 2021, which is over 500 rushing yards than the next man on the list. JT already has 29 rushing touchdowns in his young career as well (18 TDs the previous season alone), which is why he’s currently the running back with the best odds to win the 2022 NFL Offensive Player of the Year award as we speak.

Derrick Henry

  • 2022 NFL OPOY Award Odds: +1200

Not long ago, King Henry dominated the realm of offensive juggernauts. Derrick Henry, the face of the Titans franchise, won the NFL Offensive Player of the Year award in 2020 by running for over 2,000 yards and he was on pace to reclaim his OPOY throne last season before a season-ending injury derailed his campaign. The game plan remains the same in Music City, and that is to feed the two-time NFL rushing yards leader non-stop en route to re-establishing his place as the league’s best back, hands down.

Christian McCaffrey

  • 2022 NFL OPOY Award Odds: +2105/li>

Speaking of injuries, former first-team All-Pro selection Christian McCaffrey has not played a full regular season since his amazing 2019 campaign as injuries have limited him to just 10 games over the last two years. McCaffrey is still, without a doubt, the focal point of the Panthers’ offense. With a fresh start in 2022, Run CMC should be revitalized as a terrific sleeper pick to win the NFL Offensive Player of the Year award, especially with Baker Mayfield as a relative upgrade at quarterback for Carolina.

Nick Chubb

  • 2022 NFL OPOY Award Odds: +2105

Overlooked by Taylor’s dominant showing and Henry’s injury, Cleveland’s Nick Chubb somehow went under the radar as the running back with the second-most rushing yards in 2021. His mere eight rushing TDs last season isn’t a good look right now, but Chubb is in line to become the main offensive threat for the Browns this coming season. Especially more so with his team’s issues at quarterback for the better part of the entire campaign with newly-signed QB Deshaun Watson set to miss the first 11 games of the season due to his widely-covered suspension.

Dalvin Cook

  • 2022 NFL OPOY Award Odds: +2500

For three straight years, standout Vikings running back Dalvin Cook has breached the 1,000-yard rushing plateau whilst missing at least three games in each of those three seasons at that. Should Cook manage to play a full 17-game season for the first time after six seasons in the NFL, he could very well be a sneaky sleeper pick to win the 2022 NFL Offensive Player of the Year award. Minnesota’s potent offense certainly helps his case as well; albeit at the expense of the team’s more prolific passing attack.

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*All stated odds are subject to change without prior notice.