2022 NFL Week 11 Odds, Overview & Picks

By Hank Blaine • November 16, 2022

NFL Week 11 starts off with a huge matchup. On Thursday, AFC squad Tennessee heads to Green Bay to take on Aaron Rodgers and the Packers. Then on Sunday, the Saints host the Rams, the Jets look for revenge versus the Patriots, and the Chiefs throw down against the Chargers on Sunday Night Football. Monday’s matchup pits the Cardinals against the 49ers.

Check out the latest NFL odds, analysis, and free picks for eight of the best games happening in NFL Week 11.

Top 2022 NFL Week 11 Games to Bet

We've got big wins from the Chiefs and Cowboys in our latest NFL Power Rankings ????

Full 1-32: https://t.co/wveCCuBKx3 pic.twitter.com/EEUlDv63nh
— ESPN (@espn) November 22, 2022

Tennessee Titans vs. Green Bay Packers

When: Thursday, November 17th, 2022. 8:15pm EST.
Where: Lambeau Field, Green Bay, WI
NFL Odds: Titans (+3) // Packers (-3)

Green Bay rallied in their last to force overtime and then beat the favored Dallas Cowboys 31- 28. The victory signaled that the Packers’ offense may have turned a corner.

But on Thursday, there’s a chance the Pack bounces. The effort versus the Boys had to have taken something out of Green Bay. Not only that, but the Packers play a team that’s 7-2 ATS this season. Tennessee should win straight up.

2022 NFL Week 11 Pick: Tennessee Titans

Los Angeles Rams vs. New Orleans Saints

When: Sunday, November 20th, 2022. 1:00pm EST.
Where: Lambeau Field, Green Bay, WI
NFL Odds: Rams (+4) // Saints (-4)

Cooper Kupp is out until late December, which means the defending champions’ season is most likely over. Cooper isn’t just the Rams’ top wide receiver. He’s often the Rams’ only offense.

New Orleans’ first round pick tackle Trevor Penning should make his debut this week. The rest of the offensive line should be healthier than it has been in a while. But the Rams’ defense is solid. Even without Kupp, LAR covers.

2022 NFL Week 11 Pick: Los Angeles Rams

New York Jets vs. New England Patriots

When: Sunday, November 20th, 2022. 1:00pm EST.
Where: Gillete Stadium, Foxborough, MA
NFL Odds: Jets (+2.5) // Patriots (-2.5)

The Patriots won the first game behind a ferocious defense that picked off Jets starting quarterback Zach Wilson 3 times.

Since the loss, the Jets have played great, upsetting Buffalo 20-17. Wilson won’t play as badly on Sunday like he did in the first contest. The Jets should take this SU.

2022 NFL Week 11 Pick: New York Jets

Chicago Bears vs. Atlanta Falcons

When: Sunday, November 20th, 2022. 1:00pm EST.
Where: Mercedes-Benz Stadium, Atlanta, GA
NFL Odds: Bears (+3) // Falcons (-3)

Earlier in the season, the Falcons were playing great. Heading into week 11, the ATL has lost 2 straight and are on an 0-4 against the spread losing streak.

Chicago’s offense has stepped it up. Justin Fields has turned into one of the top three rushing quarterbacks in the league. The Bears scored 32 versus Miami and 30 against Detroit. Chicago all the way.

2022 NFL Week 11 Pick: Chicago Bears

Cincinnati Bengals vs. Pittsburgh Steelers

When: Sunday, November 20th, 2022. 4:25pm EST.
Where: Acrisure Stadium, Pittsburgh, PA
NFL Odds: Bengals (-3.5) // Steelers (+3.5)

When Cincinnati faces Pittsburgh, the Bengals have trouble covering the spread. Cincy is 10-22-1 ATS in the last 33 games. That’s a difficult trend to look past.

Also, the Bengals offensive line has allowed 14 sacks in 9 games and TJ Watt is back for the Steelers. In addition, this happens on Pittsburgh’s field. The Steelers cover.

2022 NFL Week 11 Pick: Pittsburgh Steelers

Dallas Cowboys vs. Minnesota Vikings

When: Sunday, November 20th, 2022. 4:25pm EST.
Where: U.S. Bank Stadium, Minneapolis, MN
NFL Odds: Cowboys (-2) // Vikings (+2)

This happens in Minnesota and the Vikings are playing great ball, but it’s difficult to back the Norsemen in this spot. Minnesota has had to rally in their last couple of games.

Also, there’s a chance Minny bounces. The Vikings were all out to beat the Bills in Buffalo in NFL Week 10. Big D wins and covers.

2022 NFL Week 11 Pick: Dallas Cowboys

Kansas City Chiefs vs. Los Angeles Chargers

When: Sunday, November 20th, 2022. 8:20pm EST.
Where: SoFi Stadium, Inglewood, CA
NFL Odds: Chiefs (-6.5) // Chargers (+6.5)

The Chiefs are just 3-5-1 against the spread this season. So there’s some reason to believe the Bolts cover.

However, KC is 8-1 ATS in the last 9 head-to-head on the road. The Chiefs love to destroy the Chargers when they face them in California. Mahomes and his mates get it done.

2022 NFL Week 11 Pick: Kansas City Chiefs

San Francisco 49ers vs. Arizona Cardinals

When: Monday, November 21st, 2022. 8:15pm EST.
Where: Estadio Azteca, Mexico City, MX
NFL Odds: 49ers (-7.5) // Cardinals (+7.5)

On paper, San Francisco is the better team. Then again, the Cards got it together in their last, beating the Rams 27-17.

The 49ers are just 4-5 ATS this season. SF has gone 1-3 against the spread in their last 4. Ah, but Kyler Murray may not play. If Murray doesn’t, 49ers cover.

2022 NFL Week 11 Pick: San Francisco 49ers

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*All stated odds are subject to change without prior notice.