With four games left in the NFL Regular Season, it’s do or die time for teams hoping to make the playoffs. Our top picks in week 15 include the surging Lions taking on the Jets, Jacksonville hosting Dallas, and the Bengals traveling to Tampa.

Check out the latest NFL odds, analysis, and free picks for eight of the best games happening in NFL Week 15.

Top 2022 NFL Week 15 Games to Bet

Brock Purdy has the 49ers climbing in our latest NFL Power Rankings ????

Full 1-32: https://t.co/jcLqk8cp1x pic.twitter.com/L2yLoqbx8r

— ESPN (@espn) December 13, 2022

READ MORE: 2022 NFL Week 15 Fantasy Waiver Wire Picks

Detroit Lions vs. New York Jets

• When: Sunday, December 18th, 2022. 1:00pm EST.
• Where: MetLife Stadium, East Rutherford, NJ
• NFL Odds: Lions (-0.5) // Jets (+0.5)

After a nice 31-10 victory over the Bears, Mike White and the Jets have since lost two straight. We can forgive the last loss, a defeat to the Bills in Buffalo.

The Jets’ recent struggles, and the Lions’ win against Minnesota in week 14, are the main reasons Detroit is a road chalk. But the Lions haven’t faced a defense as good as New York’s. On their field, J-E-T-S prevails.

2022 NFL Week 15 Pick: New York Jets

Pittsburgh Steelers vs. Carolina Panthers

• When: Sunday, December 18th, 2022. 1:00pm EST.
• Where: Bank of America Stadium, Charlotte, NC
• NFL Odds: Steelers (+2.5) // Panthers (-2.5)

It won’t matter if Kenny Pickett or Mitch Trubisky plays quarterback for the Steelers. The Panthers are in excellent form, winning two straight, covering in four straight, and covering in 6-of-7.

Sam Darnold has settled in nicely in the starter’s role under center. Carolina blows past the spread.

2022 NFL Week 15 Pick: Carolina Panthers

Dallas Cowboys vs. Jacksonville Jaguars

• When: Sunday, December 18th, 2022. 1:00pm EST.
• Where: TIAA Bank Field, Jacksonville, FL
• NFL Odds: Cowboys (-4.5) // Jaguars (+4.5)

For some reason, the Cowboys had to rally to beat the Houston Texans 27-23. Things shouldn’t get easier for the Boys.

Jacksonville looked great smashing the Tennessee Titans. Beating Dallas will be more difficult, but Jags’ QB Trevor Lawrence has gotten into a groove and the defense is playing well. Jacksonville keeps the score difference to a field goal.

2022 NFL Week 15 Pick: Jacksonville Jaguars

New England Patriots vs. Las Vegas Raiders

• When: Sunday, December 18th, 2022. 4:05pm EST.
• Where: Allegiant Stadium, Paradise, NV
• NFL Odds: Patriots (-1) // Raiders (+1)

Las Vegas blew their chance at a fourth straight victory. The Raiders had their game in the bag but couldn’t stop Baker Mayfield, a player they are somewhat familiar with having seen Baker when he was with the Browns.

On Sunday, the Raiders must contend with a decent Patriots squad. It’s going to be tough for Josh McDaniels to outcoach Master Bill. Pats get the win and cover.

2022 NFL Week 15 Pick: New England Patriots

Cincinnati Bengals vs. Tampa Bay Buccaneers

• When: Sunday, December 18th, 2022. 4:25pm EST.
• Where: Allegiant Stadium, Paradise, NV
• NFL Odds: Bengals (-3.5) // Buccaneers (+3.5)

Tampa is in total disarray. Having trouble scoring against the San Francisco 49ers’ defense is one thing.

Allowing Brock Purdy and the Niners offense to dominate is another. Cincinnati is rolling, the Bengals have won 8-of-10 and have covered in 9-of-10. So Joe Cool leads Cincy to a win and cover against the the Terrific One and the Buccaneers.

2022 NFL Week 15 Pick: Cincinnati Bengals

Tennessee Titans vs. Los Angeles Chargers

• When: Sunday, December 18th, 2022. 4:25pm EST.
• Where: SoFi Stadium, Inglewood, CA
• NFL Odds: Titans (-3.5) // Chargers (+3.5)

It’s so difficult to go against Tennessee in this spot but the Titans have so many injuries. The offensive line is a mess. The secondary is down to third string players.

The Bolts have key players injured as well. However, Mike Williams and Keenan Allen should play, which means the Chargers are the team to back to win and cover.

2022 NFL Week 15 Pick: Los Angeles Chargers

New York Giants vs. Washington Commanders

• When: Sunday, December 18th, 2022. 8:20pm EST.
• Where: FedEx Field, North Englewood, MD
• NFL Odds: Giants (+4.5) // Commanders (-4.5)

The last time these two faced off the game ended in a 20-20 draw. Washington hasn’t played since then while the Giants lost to Philadelphia 22-48.

This game happens in D.C. where Washington should have an edge. The point spread is too much, though. At -3, Washington is the play. At -4.5, we have to go with the G-Men to cover.

2022 NFL Week 15 Pick: New York Giants

Los Angeles Rams vs. Green Bay Packers

• When: Monday, December 19th, 2022. 8:15pm EST.
• Where: Lambeau Field, Green Bay, WI
• NFL Odds: Rams (+7) // Packers (-7)

Forget Baker Mayfield for a moment. Yeah, sure, Baker provided one of the most improbable pro quarterback performances in NFL history.

But Mayfield isn’t the story in this. The Packers are 5-8 ATS overall and have gone 3-7 ATS in their last 10. Laying a touchdown and extra point on a team that hates covering spreads doesn’t often lead to betting success.

2022 NFL Week 15 Pick: Los Angeles Rams

Where to Bet On NFL with Bitcoin

NFL odds are available all year round here at Nitrobetting. Create a Nitrobetting account now to win tons of Bitcoin from the 2022 NFL season with our up-to-date NFL futures odds, as well as our special Bitcoin Squares and Picks contests throughout the upcoming season!

Check out our latest sports betting guides for the 2022 NFL season. Stay tuned for more football previews and articles and don’t forget to check out the latest NFL betting odds at our online Bitcoin sportsbook.

*All stated odds are subject to change without prior notice.

READ MORE: 2022 NFL Week 14 Takeaways