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Cardinals vs. 49ers 2021 NFL Week 9 Odds, Analysis and Prediction

By Carlos Chacon

The Cardinals are set to face the 49ers this weekend. Head coach Kliff Kingsbury and company will try to bounce back on the road after picking up their first loss this season. Meanwhile, the 49ers are in high spirits after breaking their four-game losing streak last week.

NitroBetting brings you a preview of this weekend’s Cardinals vs. 49ers contest. Find every piece of information you need down below. We share essential game details, team and player statistics, and the latest NFL betting odds. More than that, we supply timely betting trends and predictions that help you lock in on the best picks. Check out the latest sports betting odds and lines at our online Bitcoin sportsbook.

Cardinals vs. 49ers Game Information

  • When: Sunday, November 7, 2021, 4:25 PM ET
  • Where: Levi’s Stadium, Santa Clara, CA
  • TV: FOX
  • Radio: 98.7 FM Arizona’s Sports Station (Cardinals) / KSAN 107.7 FM (49ers)
  • Live Stream:NFL Game Pass
  • NFL Odds: Cardinals (TBA) / 49ers (TBA)

READ MORE: Chargers vs. Eagles 2021 NFL Week 9 Odds, Preview and Pick

Why Bet on the Arizona Cardinals?

The Cardinals hold one of the best records in the league and sit on top of the NFC West division. They are tied with the Rams and the Packers at 7-1 and are one of two teams that went seven games undefeated.

Previewing the offense, we saw the Cardinals produce six 30-plus point games since the beginning of the season. The team ranks eighth in yards per game at 393.6 yards. Passing is also a strong suit of the offense. The Cardinals record 264.9 passing yards per game (10th). Additionally, they also have one of the most impressive rushing statistics in the league. At the time of this writing, the Cardinals average 128.8 rushing yards per game (seventh).

Defense is the Cardinals’ strongest suit. They hold opponents to 319.0 yards (fourth) and 17.2 opponent yards (third) per game as a team. The unit also limits opponents to 198.9 passing yards per game (fourth). However, the side has trouble dealing with rushing plays. They currently give up 24.6 opponent rushes per game (13th).

The Cardinals are plagued with injuries on the offensive end. Starting quarterback Kyler Murray (ankle), running back Chase Edmonds (shoulder), wide receiver DeAndre Hopkins (hamstring), left guard Justin Pugh (calf), and center Max Garcia (Achilles) are on the questionable list for this weekend’s matchup.

Why Bet on the San Francisco 49ers?

The 49ers recovered from a slump last week after a convincing 33-22 win against the Bears. They now hold a 3-4 record and third place in the NFC West.

The Niners recorded 467 total yards against the Bears. This brings their season averages to 369.7 yards (13th) and 246.0 passing yards (15th) per game. The positive trend means a more confident 49ers squad this weekend. More than that, the team produces promising numbers on the rushing side. The team averages 123.7 rushing yards per game (11th) and produces at least 1.4 rushing touchdowns per game (fifth).

The hosts are a defensive threat. This is where the team does the most damage. They averaged 324.0 opponent yards per game in seven games (fifth). Additionally, the side limits opponents to 196.9 passing yards per game (third). But with a defense vulnerable to rushing plays, we expect the Cardinals to utilize their carrying expertise to gain an advantage.

Four starters are on the 49ers’ questionable list. Running back Elijah Mitchell (knee), wide receiver Deebo Samuel (calf), and left tackle Trent Williams (ankle) are three players from the offensive unit that might miss the game. Meanwhile, strongside linebacker Azeez Al-Shaair is in the NFL concussion protocol after taking a hit in his most recent appearance.

Cardinals vs. 49ers Betting Trends

  • The Cardinals scored 31 points or more in four of their last five regular-season road games.
  • The Cardinals are 7-3 in their last 10 regular-season road games (7-3 ATS).
  • The totals went under in five of the Cardinals’ last ten regular-season road games against the 49ers.
  • The 49ers scored 20 points or more in three of their last five regular-season home games against the Cardinals.
  • The 49ers are 5-5 in their last 10 regular-season home games against the Cardinals (3-7 ATS).
  • The totals went over in six of the 49ers’ last ten home games.

Cardinals vs. 49ers Expert Betting Predictions

The visitors get a slight advantage in this contest. With a solid offense, they can put pressure on their opponents early on. If they put their recent loss to the Packers behind them, this is a chance to recoup some pace. However, we expect the 49ers to give the Cardinals a run for their money. They have been exceptional on this end of the field, so covering the spread should be a doable task for the side. Moreover, an outright win is not off the table for the hosts on Sunday afternoon.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.