Cardinals vs. Jaguars 2021 NFL Week 3 Odds, Preview and Pick

By Carlos Chacon • September 23, 2021

The Arizona Cardinals try to stretch their winning streak this weekend as they take on the Jacksonville Jaguars. On Sunday afternoon, both teams meet at the TIAA Bank Field and in Week 3 of the 2021 NFL season. The Cardinals look good after winning their first two games of the calendar, breezing by the Titans followed by a closely contested game against the Vikings.

Meanwhile, the Jaguars come from a loss against the Broncos and enter the game with a winless record. It’s been a strenuous couple of weeks for the team as they try to recover from the losses.

Another batch of games come our way and NitroBetting puts together previews of the most anticipated games of the weekend, featuring this Cardinals vs. Jaguars clash. Find event details, team and player statistics, and the latest NFL betting odds. Moreover, we have the latest betting trends and expert betting predictions to help you secure the best picks. Don’t forget to check out the latest 2021 NFL odds at out online Bitcoin sportsbook.

Cardinals vs. Jaguars Game Information

Now this is a story all about how
Week 2 got flipped turned upside down.
— Arizona Cardinals (@AZCardinals) September 22, 2021

When: Sunday, September 26, 2021, 1:00 PM ET
Where: TIAA Bank Field, Jacksonville, Florida
TV: FOX
Radio: Arizona Sports 98.7 FM (Cardinals) / WJXL AM 1010 (Jaguars)
Live Stream:NFL Game Pass
NFL Odds: Arizona Cardinals (-7.5) / Jacksonville Jaguars (+7.5)

Why Bet on the Arizona Cardinals?

The Cardinals escaped the Vikings in a narrow 34-33 victory last weekend. In their winning efforts, Kyler Murray recorded an incredible 400 yards on 29 of 36 passing, including 3 touchdowns and 2 interceptions. Rondale Moore was his number one target as the wide receiver ended up with 114 yards on 7 receptions and a touchdown. DeAndre Hopkins and A.J. Green did well to help their team make the game close, combining for 98 yards and a touchdown each. Moreover, Murray had the only rushing touchdown of Arizona and added 31 rushing yards.

Defensively, Jalen Thompson filed a team-high 8 solo tackles, while Budda Baker was not far behind with 8 tackles (7 solo). Markus Golden had the only sack of the unit on top of 3 tackles (3 solo). Isaiah Simmons ended his night with 8 tackles (6 solo) and proved to be a pivotal component of the Cardinals’ win. With a healthy squad, head coach Kliff Kingsbury looks forward to another great performance when they hit the road to face the Jaguars.

Why Bet on the Jacksonville Jaguars?

Currently, the Jaguars hold the last place in the AFC South and try to recover from two underwhelming games. It’s been a while since we saw the team appear in the playoffs, and head coach Urban Meyer will try to turn things around in his first year. In their losing efforts against the Broncos, Trevor Lawrence was held back to 118 passing yards on 14 of 33 passing.

The quarterback managed to score a touchdown and make 2 interceptions, but he has to step up if he wants to put pressure on the Cardinals’ defense. Marvin Jons led the receiving end with 55 yards on 6 receptions and a touchdown, while James Robinson produced 47 rushing yards on 11 carries.

Looking at the offensive unit, Laviska Shenault Jr. might miss the next game due to a suspected shoulder injury he suffered in the Jaguars’ previous game. A.J. Cann remains questionable as well, while James O’Shaughnessy is out with a sprained ankle.

On defense, Rayshawn Jenkins documented 6 solo tackles against the Broncos. Andrew Wingard follows closely with 8 tackles (5 solo) and a sack. Additionally, Adam Gotsis and Josh Allen filed the 2 other sacks in the night. C.J. Henderson is questionable for the next game after suffering a hip injury last weekend. The cornerback was able to record 4 tackles (3 solo) before stepping off the field.

Cardinals vs. Jaguars Betting Trends

The Cardinals are 2-3 in their last 5 away games.
The Cardinals are 2-3 against the spread in their last 5 away games.
The totals have gone under in 5 of the Cardinals’ last 5 games.
The Jaguars are 0-5 in their last 5 home games.
The Jaguars are 1-4 against the spread in their last 5 home games.
The totals have gone over in 2 of the Jaguars’ last 5 home games.

Cardinals vs. Jaguars Expert Betting Predictions

The Cardinals have the upper here. They did well offensively against a courageous Vikings team in their last game. And with two wins in the bag, they hold more momentum than the Jags. Meanwhile, the Jaguars have to be at their best if they want to take the win. Although there’s a good chance that the Jaguars cover the spread, we expect them to go all out to try and find win number one with the help of their home crowd.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.