Chiefs vs. Chargers 2022 NFL Week 11 Odds, Preview & Pick

By Hank Blaine • November 18, 2022

Sunday’s Kansas City at Los Angeles Chargers Week 11 matchup was originally a late-afternoon game, but the NFL decided to flex it into the Sunday night window in place of Bengals-Steelers.

These teams seem to always play tight games and they did in Week 2 in Kansas City as the Chiefs rallied for a 27-24 win. Chiefs rookie cornerback Jaylen Watson picked off Justin Herbert at the goal line early in the fourth quarter, headed the other way and was never touched on a 99-yard go-ahead touchdown that propelled Kansas City to the win. Chiefs quarterback Patrick Mahomes threw for 235 yards with TD passes to Jerick McKinnon and Justin Watson.

Herbert, who finished with 334 yards and three touchdown passes, hit Joshua Palmer in the back of the end zone on fourth-and-goal to pull Los Angeles within 27-24 with just over a minute to go. Kansas City recovered the onside kick and ran out the clock to end the game.

Nitrobetting is ready to equip its bettors with the latest news, NFL odds, and special features for the entire duration of the 2022 NFL season. This time, let’s take a closer look at the upcoming Week 11 showdown between the Kansas City Chiefs and the Los Angeles Chargers.

Chiefs vs. Chargers Game Information

The seasons change, but the work doesn't. pic.twitter.com/ATn0086c90
— Kansas City Chiefs (@Chiefs) November 17, 2022

When: Sunday, November 20, 2022, 8:20 PM ET
Where: SoFi Stadium, Inglewood, CA
TV: NBC
Radio: 700 WLW (Chiefs) // WDVE 102.5 FM (Chargers)
Live Stream: NFL Game Pass
NFL Odds: Chiefs (-4.5) // Chargers (+4.5)

Why Bet on the Kansas City Chiefs?

Kansas City won its third straight game this past Sunday, 27-17 over Jacksonville. Mahomes found four different players for scores while completing 26-of-35 passes for 331 yards, marking his league-most 12th game with 300+ passing yards and 4+ touchdowns since 2018.

Through nine games, Mahomes continues to lead the NFL in passing yards (2,936) and passing touchdowns (25). He also broke an NFL record vs. the Jags as Mahomes now owns the league mark for passing touchdowns (176) through 75 career games. He did so in only his 72nd outing. Mahomes has now won 24 consecutive games in November or December. His last loss in either month took place in 2019.

Travis Kelce caught six passes for 81 yards and a touchdown vs. Jacksonville, his fifth performance in the last six weeks with at least 80 receiving yards. The only time he didn’t hit that mark during that stretch – which was in Week 5 – he still caught four touchdowns. The All-Pro tight end is currently tied for the NFL lead in receiving touchdowns (8) and ranks seventh in receiving yards (740).

No. 1 wideout JuJu Smith-Schuster (concussion) has not practiced through Thursday. JuJu took a brutal helmet-to-helmet hit from Jags safety Andre Cisco on Sunday. He remained down on the field for a few minutes before being helped to the locker room by multiple trainers.

Why Bet on the Los Angeles Chargers?

The Chargers blew an early 10-0 lead at the 49ers last Sunday and lost 22-16, not scoring in the second half. After scoring a touchdown on their opening possession, the Chargers managed just three field goals — two on drives that started in Niners territory — the rest of the way against a stout San Francisco defense. Herbert went 21 for 35 for 196 yards with a touchdown pass for the Chargers, who were playing without both starting tackles and receivers.

The Chargers rolled out their fifth starting offensive line combination and hung in there against a tough 49ers pass rush. Guards Matt Feiler and Zion Johnson are the only Chargers offensive players to have been on the field for all 635 snaps this season.

Those two receivers, Keenan Allen and Mike Williams, both of whom have missed the past two games because of injuries, returned to practice this week. “Just kind of day-by-day now,” said Allen, who has been dealing with a left hamstring injury that has sidelined him for all but a half-game since Week 1. Williams, meanwhile, has been dealing with a high ankle sprain he suffered in the fourth quarter of Week 7. He hasn’t practiced for three weeks and aid he was looking forward to seeing how his ankle responded from Wednesday’s work.

The Bolts on Wednesday placed defensive linemen Otito Ogbonnia and Christian Covington on injured reserve and in a corresponding move signed defensive lineman Tyeler Davison from the Cleveland Browns’ practice squad. Drafted in the fifth round of the 2015 NFL Draft, Davison brings experience to the group, as he has played in 105 regular season games, 86 of those being starts.

Since that early-September loss to KC, the Chargers have remained in playoff contention despite placing edge rusher Joey Bosa, cornerback J.C. Jackson and defensive lineman Austin Johnson, along with Ogbonnia and Covington, on injured reserve.

Chiefs vs. Chargers Betting Trends

Chiefs are 1-3-1 ATS in the last 5 games overall.
Kansas City is 5-1 SU in the last 6 games.
The total went over in 7 of Kansas City’s last 8 games on the road.
Chargers are 4-1 ATS in the last 5 games following a straight up loss.
LA Chargers are 4-2 SU in the last 6 games.
The total went over in 10 of LA Chargers’ last 15 games.

Chiefs vs. Chargers Expert Betting Predictions

Chiefs 30, Chargers 27.

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*All stated odds are subject to change without prior notice.