The Colts and the Titans are meeting for the first time this season at Nissan Stadium. This weekend, Indianapolis will continue its hunt for a win following an opening game loss to the Seahawks and another narrow loss at the hands of the Rams last weekend. Meanwhile, the Titans get the support of their home crowd as they return from a road victory against the Seahawks. These are exciting times for fourth-year head coach Mike Vrabel as he tries to bring the team back into playoff contention.

As the league heads into its third week, NitroBetting puts together previews of the games to watch out for, including this Colts vs. Titans contest. Get a low down of the event’s details, important team and player statistics, and the latest NFL betting odds. Furthermore, we take it to the next level and provide timely betting trends and predictions that bring you a step closer to winning picks. Don’t forget to check out the latest 2021 NFL odds at out online Bitcoin sportsbook.

Colts vs. Titans Game Information

Kick down the door. ? pic.twitter.com/Evy1VZyPfM

— Tennessee Titans (@Titans) September 20, 2021

• When: Sunday, September 26, 2021, 1:00 PM ET
• Where: Nissan Stadium, Nashville, Tennessee
• TV: CBS
• Radio: 1070 The Fan (Colts) / WGR 550 (Titans)
• Live Stream:NFL Game Pass
• NFL Odds: Indianapolis Colts (+5.0) / Tennessee Titans (-5.0)

READ MORE: Saints vs. Patriots 2021 NFL Week 3 Odds, Preview and Pick

Why Bet on the Indianapolis Colts?

The Colts are coming off a 27-24 loss to the Rams last weekend. They did well to bounce back after a scoreless first quarter and closed the deficit down to just three points by the fourth quarter. It was a close fight in total yards as they trailed by just under 20 yards by the end of the game while winning the rushing side by 8 yards. Carson Wentz recorded 247 yards on 20 of 31 passing, including a touchdown and an interception.

Backup quarterback Jacob Eason saw playing time as well and managed to document 25 yards on 2-of-5 passing and an interception. Over at the receiving end, Michael Pittman Jr. led the pack with 123 yards on 8 receptions, followed by Jack Doyle who had 64 yards on 5 receptions. Zach Pascal is the only player to score a receiving touchdown after recording 38 yards on 5 receptions.

Eason could get the start in Week 3 for the Colts, with Wentz hurting both his ankles against the Rams. His status is worth monitoring in the coming days.

Why Bet on the Tennessee Titans?

Hosting the game this weekend are the Titans, who just scored their first win of the season against the Seahawks 33 to 30. The Titans dominated the field in total yards at 532 yards, over 100 yards more than their opponents. More than that, the Titans took the rushing game to the next level when they recorded a total of 212 yards.

Ryan Tannehill had control of the offense as he ended his night with 347 yards on 27-of-30 passing. Julio Jones was his number one target as the wide receiver documented 128 yards on 6 receptions. However, Derrick Henry made all the difference for the team, completing 182 rushing yards on 35 carries, including the only 3 touchdowns of the team.

Defensively, Chris Jackson listed a team-high 6 tackles (5 solo) with Harold Landry not far behind at 6 tackles (4 solo). Denico Autry was successful in getting 1.5 sacks and helped out Jeffrey Simmons get half of a sack, while the two combined for 4 tackles. In addition, Olasunkanmi Adeniyi wrote down a solo tackle and a sack to help his team get the victory.

Colts vs. Titans Betting Trends

• The Colts are 3-2 in their last 5 away games.
• The Colts are 4-1 against the spread in their last 5 away games.
• The totals have gone over in 4 of the Colts’ last 5 away games.
• The Titans are 1-4 in their last 5 home games.
• The Titans are 1-4 against the spread in their last 5 home games.
• The totals have gone under in 2 of the Titans’ last 5 games.

Colts vs. Titans Expert Betting Predictions

It should be a highly entertaining contest as both sides are almost at par when looking at skill and depth. The Titans get the upper hand here as they hold the home-field advantage and more momentum. Nonetheless, we can’t go over the fact that the Colts have what it takes to cover the spread. As long as the team stays composed and dictates the pace, they should be on the safer side of the spectrum.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.