Cowboys vs. Saints 2021 NFL Week 13 Odds, Analysis and Prediction

By Hank Blaine • December 2, 2021

The Dallas Cowboys and New Orleans Saints both lost last Thursday on the Thanksgiving holiday in the USA and they try again this Thursday night against one another to kick off Week 13 in the NFL from New Orleans. The Cowboys, along with the Arizona Cardinals and New England Patriots, are one of three division leaders entering this week that were not in the playoffs last season. At least two teams have won their divisions the season after missing the playoffs in 17 of the past 18 years.

Dallas is 17-13 all-time vs. New Orleans but the Saints have won nine of the past 13. They last played Week 4 of the 2019 season and the Saints won ugly 12-10. Vonn Bell had a forced fumble and two recoveries and Wil Lutz kicked four field goals. It was the first time since 1998 that the Saints won a game without scoring a TD. Ezekiel Elliott scored the game’s only touchdown in the third quarter to give Dallas a 10-9 lead. But he finished with just 35 yards and his longest run was 6 yards. Dak Prescott finished 22 of 33 for 223 yards.

Before anything else, get a look at the Cowboys vs. Saints game in this NitroBetting preview. We bring you information that covers essential event details, team and player statistics, and the latest NFL betting odds. On top of that, we share timely betting trends and predictions geared to bring you closer to the best picks. Check out for more Football odds, analysis, and a free picks at our online Bitcoin sportsbook.

Cowboys vs. Saints Game Information

When: Thursday, December 2, 2021, 8:20 PM ET
Where: Caesars Superdome, New Orleans, Louisiana
TV: FOX
Radio: KMVK 107.5 FM (Cowboys) / WWL-FM 105.3 (Saints)
Live Stream:NFL Game Pass
NFL Odds: Cowboys(-4.5) / Saints(+4.5)

Why Bet on the Dallas Cowboys?

Dallas will be without head coach Mike McCarthy and a few of his assistants in this game due to COVID. McCarthy was placed on COVID protocols Monday but continued to direct the game preparation and was involved in all of the meetings virtually during the week. Offensive line coach Joe Philbin, who has been in the COVID-19 protocol since Thanksgiving, assistant offensive line coach Jeff Blasko, who handled the main duties in last Thursday’s overtime loss to the Las Vegas Raiders, and offensive assistant Scott Tolzien will also miss the game. Right tackle Terence Steele is the only player out due to COVID.

Defensive coordinator and former Falcons head coach Dan Quinn will serve as interim head coach but offensive coordinator Kellen Moore and special teams coordinator John Fassel also will be involved.

The Cowboys lost to the Raiders last Thursday without their two top receivers in Amari Cooper and CeeDee Lamb but both are expected for this one. Cooper has been officially activated today from the COVID list, while Lamb has been cleared from a concussion. Prescott will now have his top three receivers, Cooper, Lamb and Michael Gallup on the field together for just the third time this season. Gallup missed several games injured.

Cooper has at least five receptions in each of his three career games against New Orleans. He aims for his fourth in a row on Thursday with a touchdown reception and ninth in a row in Thursday games with at least five catches. Lamb has 100-or-more receiving yards in three of his five road games this season.

Since 2016, Prescott has 12 games with at least 375 passing yards, tied with Patrick Mahomes for the most in the league over that span. He has 2,932 passing yards this season and can reach 3,000 passing yards for the fifth time in his six-year career.

Why Bet on the New Orleans Saints?

With the Saints on a four-game losing streak, they are expected to give QB Taysom Hill his first start of the season. Hill is dealing with pain caused by a partially torn plantar fascia in his foot. His foot injury has kept him sidelined for the last two games, but he’s been able to fully participate in practices this week.

The Saints’ offense doesn’t have much to lose at this point, having gone 0-4 under Trevor Siemian and crashing out of the playoff picture. Star running back Alvin Kamara missed the past three injured but should play. Kamara has 14 touchdowns (11 rushing, three receiving) in his past eight home games. Fellow RB Mark Ingram missed last week but also should play.

Cowboys vs. Saints Betting Trends

Cowboys are 6-0 ATS in their last 6 vs. NFC.
Cowboys are 5-1 ATS vs. a team with a losing record.
The total went under in 4 of Dallas’ last 5 games.
Saints are 2-5 ATS in their last 7 vs. NFC.
Saints are 3-8 ATS vs. a team with a winning record.
The total went over in 4 of New Orleans’ last 5 games.

Cowboys vs. Saints Expert Betting Predictions

2021 NFL Week 13 Pick: Saints ATS

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.