Panthers vs. Cardinals 2021 NFL Week 10 Odds, Preview and Pick

By Carlos Chacon • November 11, 2021

Both the Carolina Panthers and the Arizona Cardinals are facing huge adversity at the most critical position in football, as their respective starting quarterbacks are dealing with injuries. The Cards just proved that they’re fine without Kyler Murray at least for one week, whereas the Panthers are just about to enter unfamiliar territory with their backup taking over the offense this Sunday.

NitroBetting is ready to equip its bettors with all the latest previews and odds for Week 10 of the 2021 NFL season. This time, we look at the fascinating NFC matchup between the Carolina Panthers and the Arizona Cardinals. Find out more about the teams and the key players, event information, the latest NFL odds, and of course, helpful betting trends and expert betting predictions. Be sure to check out the latest sports betting odds and lines at our online Bitcoin sportsbook.

Panthers vs. Cardinals Game Information

We have activated TE Demetrius Harris from the Reserve/COVID-19 list.

In addition, we have signed TE Alex Ellis, LS Kyle Nelson, and WR Darrius Shepherd to the practice squad. pic.twitter.com/i7dDezQCpz
— Arizona Cardinals (@AZCardinals) November 10, 2021

When: Sunday, November 14, 2021, 4:05 PM ET
Where: State Farm Stadium, Glendale, Arizona
TV: FOX
Radio: WBT 1110 AM (Panthers) / 98.7 FM (Cardinals)
Live Stream:NFL Game Pass
NFL Odds: Panthers (+10) / Cardinals (-10)

Why Bet on the Carolina Panthers?

After snapping their lengthy losing skid in Week 8, the Carolina Panthers found themselves on the losing end of a 24-6 drubbing at the hands of the New England Patriots this past week. The Panthers are now officially under the .500 mark for the first time this season, dashing all the promise from their 3-0 start.

Sam Darnold was once again stifled by a familiar ghost from his past in Bill Belichick and the Patriots defense, as the former second-overall pick went just 16-of-33 for 172 passing yards, three interceptions, and without a single touchdown pass. Carolina’s 10 penalties that cost the team negative-83 yards in total also didn’t help the team’s cause.

On the bright side, stud running back Christian McCaffrey made his return after a five-game absence due to injury. McCaffrey racked up a total of 106 yards from scrimmage split between his 14 rush attempts and four receptions. CMC will need to be the focal point of the Panthers’ offense once more, as Darnold is expected to miss some time with a bummed shoulder himself. That leaves unproven backup P.J. Walker as their signal-caller in Week 10’s showdown against a Cards team that can’t seem to do no wrong.

Why Bet on the Arizona Cardinals?

Even with Kyler Murray and DeAndre Hopkins sidelined in Week 9 due to injuries, the Arizona Cardinals still looked impressive during their 31-17 win over the San Francisco 49ers this past Sunday for their seventh victory of the season.

Long-time NFL backup Colt McCoy emerged from Murray’s shadow and played like an all-star against the Niners defense, throwing just four incompletions in 26 pass attempts for 249 passing yards and a TD pass to running back James Conner. Speaking of Conner, the former Pittsburgh Steeler had himself quite an afternoon, as he amassed 96 rushing yards and two more trips to the end zone on the ground on 21 carries.

Murray’s week-to-week timetable dealing with an ankle injury has us believing that the MVP frontrunner of the season will miss another game just for extra precautions. But with the way that the Cards are playing regardless of who’s under center, their stout defense that ranks third in the NFL at just an average 17.2 points allowed per contest will likely be enough for the Cardinals to keep the good times rolling.

Panthers vs. Cardinals Betting Trends

The Panthers are just 3-6 in their last nine regular-season road games, but are 7-2 against the spread.
The Panthers are 3-0 against Arizona since 2016 (SU/ATS).
The totals went under in five of Carolina’s last six road games.
The Cardinals are 3-1 at home this season (SU/ATS).
The Cards are 4-1 in games wherein they’re favored to win this season (3-2 ATS).
The totals went under in each of Arizona’s last three home games.

Panthers vs. Cardinals Expert Betting Predictions

Despite the Cardinals’ injury woes, specifically to Murray, they’re currently pegged as double-digit favorites to win Sunday’s game in the desert. We’ve seen in the past how McCaffrey can easily take over any contest on his own, and that should give the Panthers more credit as a possible threat to the Cards’ magical season. If not, at the very least, put up enough points to cover the relatively wide spread.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.