Steelers vs. Bills 2021 NFL Week 1 Odds, Preview and Prediction

By Carlos Chacon • September 6, 2021

This weekend, the NFL returns to bring us much-awaited action. Among the list of games is a contest between the Pittsburgh Steelers and the Buffalo Bills. The Steelers are coming off a 12-4 record last season, claiming the top spot in the AFC North. During the preseason, the team performed wonderfully as well, ending their run with 3 wins and one loss.

Meanwhile, the Bills finished a strong run in their previous campaign with a 13-3 record and a first-place finish in the AFC East. Looking at their preseason run, the Bills also stood out with an undefeated 3-0 run.

As another football season unfolds before us, NitroBetting graces you with the latest NFL previews. Find the latest event information, key team and player stats, and the latest NFL betting odds. More than that, we make sure you lock in on the best picks with the aid of our latest betting trends and expert betting predictions. Be sure to check out the latest 2021 NFL odds at out online Bitcoin sportsbook.

Pittsburgh Steelers vs. Buffalo Bills Game Information

IT'S GAME WEEK! ?#GoBills | #BillsMafia pic.twitter.com/jMMW8UTNZ4
— Buffalo Bills (@BuffaloBills) September 6, 2021

When: Sunday, September 12, 2021, 1:00 PM ET
Where: Highmark Stadium, Orchard Park, New York
TV: CBS
Radio: WDVE 102.5 FM (Steelers) / WGR 550 (Bills)
Live Stream:NFL Game Pass
NFL Odds: Pittsburgh Steelers (+6.5) / Buffalo Bills (-6.5)

Why Bet on the Pittsburgh Steelers?

Following a solid 2020 season, the Steelers have plenty to look forward to this year. Despite showing several lapses before ending their recent campaign, they impressed everyone with an 11-0 run early into the season. Furthermore, they had a relatively short playoff run after a loss to the Browns in the Wild Card round, 48-37.

One of the defining factors in this team is their offense. They were able to match the top guns in the league and finish with a respectable record. Although they did well offensively, the team seemed to lack its more consistent ground attack as the Steelers barely tried to run the ball. Last season, they finished 31st in the league with a 34.52 rushing play percentage and dead last with only 82.5 rushing yards per game.

If they want to be more competitive this year, there should be changes made to the team. Thankfully, Pittsburgh was busy in the offseason and used a first-round pick on Alabama Crimson Tide player Najee Harris, who brings a more diverse attacking side that can stretch the field for Ben Roethlisberger and the team’s overall passing game.

Why Bet on the Buffalo Bills?

Meanwhile, the Bills show signs of strength at the end of a 13-3 run last year. Buffalo won the Wild Card Playoff game against the Indianapolis Colts and the Divisional Playoff versus the Baltimore Ravens before falling short to the Chiefs in the AFC Championship. This time around, they are back for more. The team started their preseason stint with a narrow 16-15 victory over the Lions, a blowout 41-15 victory against the Bears, while leaving the Packers scoreless 19 to nothing in their final game.

Josh Allen showed everyone how crucial his role is to the team after managing to finish with 194 yards and 2 touchdowns, while Gabriel Davis culminated his final preseason game with 75 yards on 5 receptions and a score.

Last season, Allen managed to pass for 4,544 yards and claim 37 touchdowns against 10 interceptions. Furthermore, he rushed for 421 yards and 8 touchdowns, making him the heart and soul of this team. And what makes the Bills a top contender is their ability to defend despite coming in with less depth. Buffalo’s offense averaged almost 30 points in 2020 and could deliver a strong showing against the Steelers.

Steelers vs. Bills Betting Trends

The Steelers are 2-3 in their last 5 away games.
The Steelers are 2-3 against the spread in their last 5 away games.
The totals have gone over in 4 of the Steelers’ last 5 games.
The Bills are 5-0 in their last 5 home games.
The Bills are 4-1 against the spread in their last 5 home games.
The totals have gone under in 3 of the Bills’ last 5 home games.

Steelers vs. Bills Expert Betting Predictions

Buffalo gets an advantage over the visitors in this contest. This is a rematch of Week 14 last season, and the Bills managed to secure a comfortable 26-17 win over the Steelers then. We are likely to see a similar offensive strategy coming from the favorites. However, there are plenty of reasons to back the Steelers here. They are capable of covering the spread and can even surprise us with their new offensive line. With several changes made to the team in the offseason, the results might be closer than we expected. Nevertheless, we anticipate a solid matchup between the two teams this weekend.

Check out our latest sports betting guides for the 2021 NFL Regular Season. Stay tuned for more Football previews and articles and don’t forget to check out the latest Football betting odds at our online Bitcoin sportsbook.

*All odds stated are subject to change without prior notice.